Alpha lipoic acid
R-alpha lipoic acid - Sodium R-lipoate (elemental) - 50 mg
In the form of R-Lipoic Acid Sodium Salt - 62,5 mg
Alpha lipoic acid is found in every human cell, more specifically in the mitochondria.
There, the substance is essential for the production of energy. In addition, alpha lipoic acid is an antioxidant with several benefits: it is water and fat soluble, it crosses the blood-brain barrier, and it is converted to dihydrolipoic acid, which is also an antioxidant. Alpha lipoic acid has an influence on NRf2 and ROS, which results in a better osteoblast / osteoclast ratio and improves the quality of tissues.
Alpha lipoic acid is an antioxidant that occurs in small amounts in our diet and is also produced by our liver. The body's own production decreases as we get older. There are two forms of alpha lipoic acid, the body's own R-form and the synthetic S-form. The R-form is also found in food (liver, spinach, broccoli, ...).
Since the health-promoting effects are almost exclusively attributed to the R-form, the capsule contains alpha lipoic acid in the form of Sodium R-lipoate. Bodhi follows the general advice dose of 50 mg per day.
Sources(1) Haritoglou, C., Gerss, J., Hammes, H. P., Kampik, A., & Ulbig, M. W. (2011). Alpha-lipoic acid for the prevention of diabetic macular edema. Ophthalmologica, 226(3), 127–137. https://doi.org/10.1159/000329470
(2) Song, K. H., Lee, W. J., Koh, J. M., Kim, H. S., Youn, J. Y., Park, H. S., … Park, J. Y. (2004). α-Lipoic acid prevents diabetes mellitus in diabetes-prone obese rats. Biochemical and Biophysical Research Communications, 326(1), 197–202. https://doi.org/10.1016/j.bbrc.2004.10.213
(3) Xiao, C., Giacca, A., & Lewis, G. F. (2011). Short-term oral α-lipoic acid does not prevent lipidinduced dysregulation of glucose homeostasis in obese and overweight nondiabetic men. American Journal of Physiology-Endocrinology and Metabolism, 301(4), E736–E741. https://doi.org/10.1152/ajpendo.00183.2011